The error message at the bottom of the screen says: "failed to generate new wallet: Wrong Device Status : SW=6e00 (EXPECT=9000, MASK=ffff)"
This is with Monero GUI v0.14.0.0 and a Ledger Nano S updated to firmware v 1.5.5 on a Win 7 machine.
I tried the different solutions regarding the USB driver issues as prescribed on this answer in this thread: https://monero.stackexchange.com/a/10182/10014
but it's still not working. When I plug in the Nano, the Device Manager screen updates and two new items are added: a 'Nano S' item under 'Other devices' and a 'USB Composite Device' under 'Universal Serial Bus controllers'.
I updated the driver on each one, right-clicking and searching for the driver under 'C:\Windows\winsxs' but still no dice. After the search, the message says "USB Composite Device - best driver already installed".
HarryTheHorse, the poster, mentions that the new item should show up under Smart card readers as a Microsoft Usbccid Smartcard Reader. I had the 'Smart Card' service turned off - I have a lot of unused services turned off for security reasons - but even with it on, the Device Manager does not show a 'Smart card readers' node and when I plug in the Nano and input the key, the same items show up and no 'Smart card reader' item.
Here are some screenshots:
Comodo AV and it quarantined a bunch of monero components/exes, screenshot below. I'll try to redo the drag/drop and see if I can 'allow' install of these components.