Whonix has added Monero to its APT repository (you can see that here) so the process is now pretty straightforward:
Download and add the Whonix signing key:
wget https://www.whonix.org/patrick.asc
sudo apt-key --keyring /etc/apt/trusted.gpg.d/whonix.gpg add ~/patrick.asc
Add Whonix's APT repository:
echo "deb https://deb.whonix.org busterbullseye main contrib non-free" | sudo tee /etc/apt/sources.list.d/whonix.list
Note: This line previously said "buster" instead of "bullseye" - buster is the old release - see Whonix 15 Deprecation for details
Update your package lists:
sudo apt-get update
Install the Monero GUI:
sudo apt-get install monero-gui